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More About Topical Hyperbaric Oxygen Therapy (THOT®)
Two major advantages for healing with THOT® are (1) healing without scarring and (2) no recurrence of yellow necrotic slough during the healing process. These are illustrated in the following examples.
Healing with Minimal or No Scar Tissue Formation
Wounds treated with THOT® heal with abundant vascular granulation tissue and minimal or no scar formation.
Clinically, scar formation in wounds is diagnosed by the presence of induration, associated with loss of pigmentation of the tissues around the ulcer. In wounds treated with THOT®, there is no induration or loss of pigmentation.
In many ulcer locations, such as the heel, abundant growth of granulation tissue with THOT® replaces the heel pad and causes no deformity in the heel. By contrast in tissues healed by other techniques, there is often loss of fat and underlying tissues, with replacement by scar tissue. This causes the bone to approximate the overlying skin. In ulcers situated over the heel, this loss of tissue creates the “cut-from-the-sabre” deformity in heel ulcers treated with standard wound care.
No induration or loss of pigmentation corresponds to histological findings of abundant growth of new blood vessels without significant fibroblastic proliferation. Wounds treated with standard therapies show a paucity of blood vessels and abundant fibroblastic proliferation histologically and scar tissue formation clinically.
No Recurrence of Yellow Necrotic Slough
There is no reformation of yellow necrotic slough after the first few days of treatment in wounds treated with THOT®. This contrasts with the persistent recurrence of yellow necrotic slough seen in ulcers treated with a variety of techniques.
